First of all I am so glad we're back to football at last! The long drought is over!
In my opinion, the key match up will be the Sammy Watkins vs. Jimmy Smith. I am expecting Dean Pees is planning to give Jimmy help over the top to minimize Watkins big play threat. I will always have faith in our defense to be stout against the run, especially with Sizzle fired up to get back on the field. Tyrod is an X factor, over the past couple years we haven't been strong against mobile QBs but I'm hoping that our youth infusion mixed with maybe knowing some of Tyrod's tendencies will work out for us here.
On the offensive side of the ball it has to just be about execution. I'd love to see Joe just spread the ball around, particularly getting some touches for Pitta, S.S.Sr and Perriman as it's their first game back at The Bank (or first game ever at home!!) after long injuries. No Dixon at RB but Forsett, West and Buck Allen are good backs if the line can open up some holes for them.
I think we win but don't be surprised if it's a close one, I don't expect the Bills to be pushovers. I feel we have the edge as we're at home and have so many key players coming back to the team with something to prove. Here's to a good game and no injuries on either side!